Parkinson’s Disease, Microglia, and Extracellular Matrix Remodeling
It is suggested that microglia-mediated ECM remodeling serves as a mechanistic link between neuroinflammation and neuronal susceptibility in PD.
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It is suggested that microglia-mediated ECM remodeling serves as a mechanistic link between neuroinflammation and neuronal susceptibility in PD.
A neuroglial framework for HD is defined that opens a plausible path toward meaningful disease modification and positions HD as a model disorder for glial-centric interventions in neurodegeneration.
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