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Nur Hani Hani Zainal

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Open access Aug 2026

Predicting six-year depression trajectories in adulthood: A super learner ensemble approach using the Add Health dataset.

BACKGROUND Depression is a leading global cause of disability, and much focus has been directed toward identifying population-wide predictors of adult depression. The present study aimed to identify the strongest predictors of future depression severity using a comprehensive panel of biopsychosocial predictors and the...

Jordan W J Chng, Kean J. Hsu, Nur Hani Hani Zainal · 0 citations
Open access Aug 2026

Sleep fragmentation and heightened inflammation: A latent profile subtype predicting nine-year major depressive disorder severity in the MIDUS study

Background Cross-sectional and standard approaches to examining proinflammatory activity and sleep disturbances separately hinder understanding of their additive, long-term impacts on major depressive disorder (MDD). The current study used latent profile analysis (LPA) to identify multimodal neuroimmune profiles and to...

Nur Hani Hani Zainal, S. Beaudreau · 0 citations
Open access Aug 2026

Blunted Diurnal Cortisol Slope as a Risk Marker for 9-Year Executive Function Decline: Amplification by Daily Stress and Worry Severity.

OBJECTIVES Cortisol dysregulation, reflective of hypothalamic-pituitary-adrenal (HPA) axis dysregulation, has been linked to executive functioning (EF) decline. However, substantial effect-size heterogeneity across studies highlights the potential role of psychosocial moderators. We investigated whether the severity of...

Nur Hani Hani Zainal, Stephanie Noble · 0 citations
Open access Aug 2026

From allostasis to addiction: Cortisol dysregulation, daily stress and relations with 9-year alcohol and substance use disorder severity in community adults.

Nonlinear interactions between cortisol indices and daily stressor severity appear to predict 9-year alcohol use disorder and substance use disorder severity, with cortisol area under the curve emerging as the most robust indicator.

Nur Hani Hani Zainal, Natalia Van Doren · 0 citations

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