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Nykola C. Jones

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Open access Aug 2026

Towards a molecular understanding of the role of helix 8 in GPCR trafficking.

A proposed mechanism in which helix 8 functions as a surface-active amphipathic element that promotes membrane binding, senses membrane curvature, and thereby facilitates GPCR trafficking is examined, supporting a broader model in which surface-active amphipathic motifs tune membrane protein trafficking by coupling dyn...

Tommas Theiss Ehler Nielsen, J. H. Schmidt, Samir Mustafa et al. · 0 citations

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