Some of the advantages of familial data using the Norwegian Mother, Father and Child Cohort Study (MoBa), a population-based cohort of parents and offspring with extensive genotype data, are illustrated along with broad and longitudinal phenotyping of health and functioning.
E. Corfield, A. Shadrin, O. Frei et al.· Nature· 3 citations
Early-childhood temperament is associated with later mental health. Temperament continues to develop throughout the first years of life, and a single assessment cannot capture its trajectory. Whether departures from an individual's developmental trajectory carry psychiatric risk remains unknown. Using data from more th...
J. Kopal, N. Bakken, P. Parekh et al.· Molecular Psychiatry· 0 citations
Despite great progress on case–control polygenic prediction, an unmet need remains for a method that genetically distinguishes clinically related disorders (e.g., schizophrenia (SCZ) versus bipolar disorder (BIP) versus major depressive disorder (MDD) versus controls). We introduce differential diagnosis–polygenic risk...
W. Peyrot, G. Panagiotaropoulou, L. O. Olde Loohuis et al.· Nature Genetics· 0 citations
