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Open access Sep 2026

Minimal CBX3-Derived UCOE Confers Long-Term Resistance to Transgene Silencing in Human iPSCs During Neuronal Differentiation

It is demonstrated that considerable UCOE minimization can be achieved without markedly compromising anti-silencing activity, providing a potential vector-design advantage by reducing the regulatory cassette footprint and increasing available vector capacity.

O. Anakok, G. Akcay · 0 citations

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