O. B. Ogunleke

Nanoparticle-antibiotic synergy against bacterial biofilms: mechanisms, therapeutic potential, and future directions

Bacterial biofilms pose significant challenges in clinical and industrial settings because of their resistance up to 1000-fold higher than that of planktonic bacteria. This resistance arises from extracellular polymeric matrix, reduced metabolic activity, and horizontal gene transfer. The growing burden of biofilm-asso...