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O. Benslama

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Oct 2026

Antimicrobial and Antioxidant Potential of Specialized Metabolites From Rubus ulmifolius Schott: A Combined Experimental and Computational Approach

The specialized metabolite profile of Rubus ulmifolius Schott leaves collected in Algeria was investigated, and their biological activities were evaluated using complementary in vitro and in silico approaches. Leaf extracts were obtained by maceration followed by n ‐hexane and dichloromethane fractionation, as...

A. Bramki, G. Barboucha, O. Benslama et al. · 0 citations
Open access Sep 2026

Volatilome and derivatized metabolome via GC-MS of Heliotropium europaeum: antioxidant potential and anti-inflammatory activity with in-silico study

Heliotropium europaeum is a medicinal plant traditionally used for the treatment of inflammatory and skin disorders; however, t he volatile and derivatized metabolomic composition of the Algerian population remains largely unexplored. In this study, the volatile and derivatized metabolite composition of the aeri...

Roukia Zatout, O. Benslama, Manar Mekki et al. · 0 citations
Sep 2026

Design and synthesis of novel 4-substituted 1,4-dihydropyridine (DHP) derivatives, molecular docking and anti-oxidant activity

Abstract A new series of 1,4-dihydropyridine derivatives bearing a benzoic acid at the N-position were prepared by Hantzsch syntheses with piperidine as the catalyst, enamine of dimedone and 2-benzylidenemalononitrile as starting materials. Various substituted substrates were successfully used, affording the N-substitu...

Heythem Bentamene, O. Benslama, Ramzi Maadadi et al. · 0 citations
Open access Aug 2026

Phytochemical profiling and insecticidal activity of Moricandia sinaica across growth stages: experimental and molecular docking insights.

BACKGROUND Stored food products are highly vulnerable to infestation by insects and mites, resulting in significant postharvest losses worldwide. Plant-derived bioactive compounds represent promising eco-friendly alternatives to synthetic pesticides. This study investigated the phytochemical composition of Moricandia s...

Roukia Zatout, O. Benslama, Chaima Zatout et al. · 0 citations
Aug 2026

Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation and ADMET Analysis Predict the Molecular Mechanisms of Gomisin N and Schisandrin B as Multi-Target Agents in Primary Sclerosing Cholangitis

Computational support is provided for the potential role of Gomisin N and Schisandrin B as multi-target candidates in PSC-related therapeutic research, although experimental validation is required to confirm their biological activity, pharmacokinetic behavior, and safety.

Nedjwa Mansouri, O. Benserradj, O. Benslama et al. · 0 citations

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