Heterologous adenovirus A2/Leish-Tec® vaccination strategy in a murine model of visceral leishmaniasis: Potential canine vaccine with enhanced protection and potent T-cell immunity.
Zoonotic visceral leishmaniasis caused by Leishmania infantum is the most severe clinical form of leishmaniasis and remains endemic in multiple regions, where it can be fatal if untreated. Domestic dogs act as the main urban reservoirs, sustaining zoonotic transmission. This study evaluated the immunogenicity and abili...