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O. Crook

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Open access Aug 2026

Population-scale subcellular proteomics reveals intracellular remodelling across the Alzheimer’s disease-resilience spectrum

Comparative subcellular proteomics applied to dorsolateral prefrontal cortex from 75 individuals spanning the Alzheimer’s disease-resilience spectrum is developed, modelling protein localisation across disease.

Helen A. Jolly, Paula Seghers, Kaleah Balcomb et al. · 0 citations
#artificial intelligence Preprint Aug 2026

Efficient Auto-Interpretability of AI Models in Biology

Cross-seed dictionary stability prioritisation finds interpretable latents using about 4.4 times fewer latent evaluations each, and at 5.2 times lower measured cost, while recovering over half of them, and the external check shows the surfaced motifs are significantly enriched for their claimed annotations.

Piotr Jedryszek, O. Crook · 0 citations

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