Sep 2026
A Community-Driven Single-Cell PBMC Reference Integrating Landmark Datasets Spanning Health and Disease
A. Cujba, Sergio Aguilar-Fernández, Adrien Y. Antoinette et al.
· bioRxiv · 0 citations
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Open access
Aug 2026
TIM3 blockade with hypomethylating therapy restores NK-cell and cytotoxic CD4+ T-cell activity in patients with AML or MDS.
The results suggest that anti-TIM3 combined with decitabine engages a distinct mechanism of immune activation compared to anti-PD1 and anti-CTLA4, preferentially expanding NK-cell and CD4+ T-cell populations.
Jani Huuhtanen, S. Forstén, B. Ford et al.
· Cancer immunology research · 0 citations