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Open access Sep 2026

Interconnections with and within the trypanosomal respiratory chain revealed by complexome profiling

Proteins are frequently integrated into multicomponent complexes that execute the elaborate processes supporting life. Thus, a protein’s function can only be defined by the company it keeps within a complex. Proteomes provide informative protein inventories but lack information about protein quaternary structures. Comp...

Corinna Benz, R. Khan, Michael Hammond et al. · 0 citations
Open access Aug 2026

A p32 family RNA editing factor acts in mitochondrial ribosome biogenesis

Biogenesis of mitochondrial ribosomes (mitoribosomes) in the unicellular parasite Trypanosoma brucei requires an exceptionally large toolkit of assembly factors, identified in stable precursors of large and small mitoribosomal subunits (mtLSU and mtSSU) by cryoEM. Here, using genetic modifications and proteomic charact...

Prashant Chauhan, Ingrid Sveráková-Škodová, J. T. Wong et al. · 0 citations

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