Review
Open access
Aug 2026
The specificity trap in routine tumor biomarker interpretation: Advancing the 3PM-based clinical decision framework to benefits of patients
A predictive, preventive, and personalized medicine (3PM)-guided clinical decision framework for interpreting routinely used tumor biomarkers is developed, shifting routine biomarker use from reactive testing and diagnostic escalation toward context-corrected interpretation, prevention of low-value investigations, and...
P. Kubatka, Ludmila Filkova, I. Slaninová et al.
· The EPMA Journal · 0 citations