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O. Kopach

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Review Open access Sep 2026

Piezo1 in Peripheral and Central Sensitisation: Implications for Chronic Pain

Piezo1 is an increasingly recognised mechanosensitive ion channel that transduces mechanical forces into electrical and biochemical signals and is expressed in peripheral sensory pathways as well as across multiple cell types within the central nervous system. Growing evidence indicates that Piezo1 contributes to nocic...

O. Kopach · 0 citations
Aug 2026

Sensory experience drives glutamate spillover, presynaptic LTP and functional connectome remodeling in the barrel cortex

Neural-network simulations suggest that volume-transmitted excitatory signals can improve associative memory retrieval in sparsely connected networks and point to a potential computational consequence of glutamate spillover for brain circuit function.

O. Kopach, James P. Reynolds, Thomas P. Jensen et al. · 0 citations

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