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Author

O. Langford

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Review Open access Sep 2026

Research satisfaction among participants in a preclinical Alzheimer's disease trial

Empirical data capturing participants’ experiences in preclinical Alzheimer's disease (AD) trials are limited. We examined participant responses on a Research Satisfaction Survey (RSS) from the Anti‐Amyloid Treatment in Asymptomatic AD Study.

Marina Ritchie, K. Hussen, O. Langford et al. · 0 citations
Review Open access Sep 2026

More efficient screening for preclinical Alzheimer's clinical trials using mixture of experts

Blood plasma biomarkers identifying Alzheimer's disease (AD) neuropathology offer accessible and scalable alternatives to lumbar puncture and positron emission tomography (PET) scans, with potential efficiency gains in clinical trial recruitment.

O. Langford, R. Raman, P. Aisen et al. · 1 citation
Open access Jul 2026

Prognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment.

Higher plasma p-tau217 levels were consistently associated with increased risk of clinical progression and accelerated cognitive decline, and support the potential of p-tau217 for prognostic model development, with direct implications for future trial design.

R. Buckley, D. Townsend, C. Birkenbihl et al. · 3 citations

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