Author

O. Ortega-Recalde

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Open access Aug 2026

Single-Cell RNA-Seq Reveals Chromosomal Instability-Associated Transcriptomic Profiles in Breast Cancer

Background/Objectives: Breast cancer (BC) is the most frequently diagnosed malignancy and a leading cause of cancer-related mortality in women worldwide. This disease is highly heterogeneous and dynamic, and chromosomal instability (CIN) plays a key role in the acquisition of these traits by generating genetic diversit...

María Paula Meléndez-Flórez, N. Rangel, Milena Rondón-Lagos et al. · Biomedicines · 0 citations

Open access Sep 2026

Gonadal remodelling in socially driven sex change is associated with novel and known sex genes, epigenetic reprogramming, and inflammation-mediated apoptosis

To characterise the molecular changes associated with gonadal metamorphosis in spotty, genomic and transcriptomic approaches are used, generating a high-quality genome and a transcriptomic time-series that captures the sex change process from start to finish, revealing distinct transcriptional profiles that characteris...

Chloé A. van der Burg, A. Goikoetxea, S. Muncaster et al. · bioRxiv · 0 citations