Circulating miR-21-5p and miR-223-3p as diagnostic biomarkers for rheumatoid arthritis in a sub-Saharan African cohort: a hospital-based case-control study.
BACKGROUND Diagnosing rheumatoid arthritis (RA) remains challenging, particularly in resource-constrained settings. Circulating microRNAs (miRNAs) have emerged as candidate non-invasive biomarkers; however, their expression in African populations has not been systematically evaluated. METHODS This hospital-based stud...