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Review Open access Sep 2026

Targeting the Siglec/sialic-acid axis in glioblastoma: Glycome-mediated immune evasion and emerging therapeutic platforms

Abstract Despite encouraging advances in cancer immunotherapy, several malignancies leverage resistance pathways to escape the effects of treatment. Abnormal cell signaling and cytokine secretion modulated by cancer cells promote a tumor microenvironment (TME), wherein the efficacy of infiltrating immune cells is dimin...

David Lee, William ElNemer, O. Selim et al. · 0 citations
Review Aug 2026

The effects of postoperative neurological deficits on overall survival in patients with malignant peripheral nerve sheath tumors.

OBJECTIVE Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas with peripheral nerve differentiation. Surgical management of MPNSTs entails wide resection with negative margins, although the extent of resection required to achieve oncological control may result in postoperative neurological morbidi...

Melanie Alfonzo Horowitz, J. Khalifeh, Xinlan Yang et al. · 0 citations

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