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Open access Aug 2026

Divergent neurobehavioral signatures of anxiety and depression: a multilevel comparative analysis in adult zebrafish

Abstract Background: Stress-related psychiatric disorders such as anxiety and depression require robust preclinical models for mechanistic exploration. In this study, we utilized adult zebrafish (Danio rerio) to investigate behavioral, molecular, and metabolic differences between anxiety- and depression-like states. Me...

Meryem Kankaynar, H. Ceyhun, E. Sulukan et al. · 0 citations
Open access Sep 2026

Early Neuroprotective Effects of Erucic Acid and Gentisic Acid on Hippocampal Glutamate Concentrations and Alzheimer-like Molecular Alterations in an Intracerebroventricular Streptozotocin Rat Model

Background: Alterations in glutamatergic homeostasis have been implicated in Alzheimer’s disease, but the relationship between total hippocampal tissue glutamate and Alzheimer-like molecular alterations remains unclear. This study evaluated the early neuroprotective potential of gentisic acid (GA) and erucic acid (EA)...

Ibrahim Gecili, M. Ertuğrul, I. Okkay et al. · 0 citations

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