Author

O. Türeci

1 paper indexed here

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Open access Sep 2026

Messenger RNA delivery of a dual CD25/CD122 affinity-tuned IL-2 variant prolongs exposure and potentiates antitumor T cell immunity

Preclinical results validate a rational design approach to overcome the limitations of IL-2 therapy and support the clinical evaluation of Alb–IL-2var RNA-LNP for solid cancers.

Mathias Vormehr, L. Kranz, A. Muik et al. · Science Advances · 0 citations