Natural load-bearing tissues derive mechanical performance from sequential self-assembly, in which collagen fibrils first compact and are then stabilized by enzymatic covalent crosslinking. Replicating this design in synthetic hydrogels while limiting swelling and preserving toughness and viscoelasticity remains challe...
Patrick Shakari, Christos Leliopoulos, Hamidreza Mokhtari et al.· Small· 0 citations
It is demonstrated, for the first time, that hydrogel formation can occur solely from carbodihydrazide-modified HA, without the need for an aldehyde-functionalized counterpart.
Shima Tavakoli, M. Shokri, Yu-Lai Xia et al.· Journal of Controlled Releas...· 0 citations
A modular bioconjugation system using polyphenol radical crosslinking, where gallic acid (GA)-modified glycosaminoglycans rapidly crosslink with diverse biomolecules under blue light and riboflavin enables the creation of customizable, cell-compatible matrices for tissue engineering and 3D cell culture.
Austin D. Evans, R. P. Parvathaneni, Rolle Rahikainen et al.· Cell Reports Physical Scienc...· 0 citations
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