Introduction: Gastrointestinal dysfunction is common in critically ill patients and is associated with increased morbidity and mortality. Plasma citrulline, a non-proteinogenic amino acid synthesized by enterocytes, has been proposed as a biomarker of intestinal function and enterocyte mass. However, the available evid...
Oana Frandeș, A. Lazăr, Sergiu-Ioan Frandes et al.· Diagnostics· 0 citations
Apoptosis plays an important role in sepsis-associated immune dysfunction, particularly through lymphocyte depletion and the development of persistent immunosuppression. This review examines apoptosis-associated biomarkers in sepsis, distinguishing relatively direct markers of cell death from complementary indicators o...
O. Coman, L. Azamfirei, Oana Frandeș et al.· Biosensors· 0 citations
AI has considerable potential to support AMR prediction and antimicrobial stewardship, but broader implementation will require rigorous validation, integration into clinical workflows, continuous monitoring and demonstration of clinical benefit.
Oana Frandeș, L. Azamfirei, Oana-Elena Branea et al.· Medicina· 0 citations
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