Author

Ofir Shorer

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Open access Oct 2026

Revealing pan-cancer clonal niches of T cells from single-cell RNA sequencing using contrastive learning

CloneTrast enables scalable and interpretable inference of clonal organization from single-cell transcriptomes and uses paired scRNA/TCR-seq during training to learn clonal-functional states from gene expression, while requiring only scRNA-seq at inference.

Ofir Shorer, Asaf Pinhasi, Ron Amit et al. · bioRxiv · 0 citations