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Author

Okan Aykaç

2 papers indexed here

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Open access Aug 2026

Investigation of the Bcl-2 Inhibition Potential of Drugs Withdrawn from the Clinic Using in silico Methods

Apoptosis is essential for tissue homeostasis, and its dysregulation is a hallmark of cancer. The B-cell lymphoma-2 (Bcl-2) protein family, particularly known for its anti-apoptotic role, contributes to tumor survival and chemoresistance. Venetoclax, a selective Bcl-2 inhibitor, has shown notable clinical success; howe...

Okan Aykaç, İrem Bozbey Merde · 0 citations

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