Author

Olga Ciccarelli

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Open access Aug 2026

Acute Attack Treatment Escalation and Subsequent Relapse Risk in Pediatric Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease

Objectives Acute treatment for myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) includes high-dose IV methylprednisolone (IVMP), with escalation to IV immunoglobulin (IVIG) and/or plasma exchange (PLEX) based on severity or incomplete response. We evaluated whether escalation at first attack infl...

Silvia Bartolomeo, Riccardo Nistri, N. Kim et al. · Neurology · 0 citations

Review Open access Aug 2026

De-Escalating and Discontinuing Immunotherapies in Patients With NMOSD and MOGAD

Treatment de-escalation is sometimes necessary because of adverse effects, comorbidities, infections, treatment fatigue, or life circumstances such as pregnancy, but in pregnancy, management requires balancing maternal disease control with fetal safety, with strategies ranging from continuation of selected therapies to...

Y. Hacohen, G. Androdias, G. Arrambide et al. · Neurology · 0 citations