Author

Oliver Limbo

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Aug 2026

Ultrasensitive circulating tumor DNA analysis improves detection of molecular residual disease in locally advanced esophageal cancer.

PURPOSE Circulating tumor DNA (ctDNA) could be a powerful prognostic biomarker for patients with locally advanced esophageal cancer but higher sensitivity is needed. An ultrasensitive test could enable improved treatment decision-making by accurately identifying patients with residual disease. EXPERIMENTAL DESIGN 331...

J. Rhoades, Anuj K. Patel, K. Xiong et al. · Clinical Cancer Research · 0 citations

Open access Aug 2026

Directed evolution of a stem-helix–targeting antibody enables MERS-CoV cross-neutralization through enhanced binding affinity

The isolation of a human monoclonal antibody from a SARS-CoV-2 convalescent donor that targets the conserved S2 stem helix region is reported, demonstrating the potential of in vitro affinity maturation to expand the neutralization breadth of stem-helix-targeting antibodies across divergent betacoronaviruses.

Panpan Zhou, M. Yuan, Yue-Xiu Zhang et al. · PLoS Pathogens · 0 citations