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Author

Oluwabukunmi M. Oluwaniran

2 papers indexed here

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Review Open access Sep 2026

Extrachromosomal DNA in Adaptive Tumour Evolution: Mechanisms Driving Plasticity, Drug Resistance and Precision Oncology

Extrachromosomal DNA (ecDNA) has been identified as a critical component of tumour evolution, offering a dynamic genetic and regulatory landscape through which cancer cells can alter oncogene dosage, transcriptional states, and cellular phenotypes. Lacking centromeric and telomeric sequences, ecDNA is inherited in a no...

Verity Ghansah, Yemisi Omotoyosi Adetayo, Oluwabukunmi M. Oluwaniran et al. · 0 citations
Review Open access Aug 2026

CRISPR Functional Genomics in Precision Oncology: Integrating Single-Cell Multi-Omics for Cancer Vulnerability Discovery

A new conceptual model is introduced, called the Integrated Functional Precision Oncology (IFPO) Framework, that brings together functional genomic perturbation, single-cell multi-omics, computational systems biology, and clinical translation and offers directions for further progress of precision cancer treatment base...

O. Oluwadare, M. Frankpeace, Oluwabukunmi M. Oluwaniran et al. · 1 citation

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