Fast-Dissociating High-Supply Peptides as Contributors to MHC-I Antigen Presentation
The major histocompatibility complex class I (MHC-I) immunopeptidome is dynamic and determined by numerous biochemical and cellular features. Computational tools to predict peptide–MHC-I binding focus on the affinity of a specific peptide–MHC interaction; separate tools predict complex stability or presentation. Method...