Recurrent Male-Selective Perinatal Death in a Family with a Paternal Yqh+ Y-Chromosome Heterochromatin Variant: A Case Report and Hypothesis [R1]
Background: Heterochromatin variants of chromosome Y (Yqh+) are classified by international cytogenetic nomenclature as benign polymorphisms. However, several case-control studies have reported a higher frequency of these variants among couples with recurrent pregnancy loss, and a plausible sex-specific mechanism ha...