Author

Ozkan Aksakal

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Sep 2026

CUMYL-4CN-BINACA exposure is associated with oxidative stress, ER stress-related responses, apoptosis, and altered KIM-1, NGAL, and Nephrin expression in rat kidney.

CUMYL-4CN-BINACA (C-4CN-B), a potent synthetic cannabinoid (SC), is linked to severe systemic toxicity, but its renal molecular toxicity remains unclear. This study examined C-4CN-B-induced nephrotoxicity in male Sprague-Dawley rats, focusing on oxidative stress, inflammation, ER stress, and apoptosis. Thirty-two rats...

Esra Aktas Senocak, Ozkan Aksakal, Cihan Gür et al. · Food and Chemical Toxicology · 0 citations