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Open access Jul 2026

Amantadine-induced reorganization of model SARS-CoV-2 lipid envelopes

Results show that amantadine interactions with simplified SARS-CoV-2 lipid envelopes depend on both the net charge of the lipid headgroup and the membrane organization, which is influenced by the presence or absence of unsaturated alkyl chains in the hydrophobic region.

M. Mierzejewska, Izabella Leszczyńska, Gabriela Węsierska et al. · 0 citations