BACKGROUND AND OBJECTIVES
To investigate the association between serum levels of glial-related biomarkers, including glycoprotein nonmetastatic melanoma B (GPNMB), soluble triggering receptor expressed on myeloid cells 2 (sTREM2), galectin-3, serpin peptidase inhibitor clade A member 3 (SERPINA3), chitotriosidase-1 (CH...
M. Comabella, Luca Bollo, N. Fissolo et al.· Neurology(R) neuroimmunology...· 0 citations
Spinal cord (SC) damage is central to multiple sclerosis (MS) progression but remains difficult to quantify with conventional magnetic resonance imaging (MRI).
To characterize upper cervical SC pathology using quantitative MRI (qMRI) and assess longitudinal changes and predictors of clinical progression and...
Kornelius Kaim, M. Ocampo-Pineda, C. Tsagkas et al.· Multiple Sclerosis Journal -...· 0 citations
The findings suggest that neuroaxonal and astrocytic stress is a component of adolescent psychopathology, particularly in AN, and sNfL appears sensitive to starvation-related neurobiological changes, with levels normalizing alongside weight restoration.
Marc Pawlitzki, L. Masanneck, L. Schlarbaum et al.· Translational Psychiatry· 0 citations
It is found that anti-CD20 B cell depletion was associated with increased frequencies of regulatory mucosal-derived IgA-producing B cells in the periphery and CSF, together with increased B cell receptor clonal overlap between mucosal and systemic compartments, indicating enhanced trafficking of IgA B cells from gut mu...
T. Neziraj, Elisabeth Pössnecker, Angela A. Wang et al.· Science Translational Medici...· 0 citations
It is suggested that serum GFAP may serve as a biomarker for personalized risk stratification and treatment monitoring and as a screening tool to reduce cohort size in clinical trials targeting MS progression.
M. Einsiedler, S. Sandgren, S. Schaedelin et al.· JAMA Neurology· 0 citations
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