Author

P. Brennan

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Open access Oct 2026

127 Clinical translation of advanced MR spectroscopy as an imaging biomarker for IDH-mutations in lower-grade gliomas

Diffuse gliomas, the most common adult primary brain tumour, are classified by their histological, genetic, and molecular characteristics. Isocitrate dehydrogenase (IDH) mutations correlate with longer mean survival and progression-free survival time. IDH mutations lead to tumour metabolic changes and the product...

M. Thrippleton, P. Brennan, Imran Liaquat et al. · Neuro-Oncology · 0 citations

Review Open access Oct 2026

Modern multidisciplinary management of brain metastasis.

Brain metastases (BrM) are no longer considered to be a uniform end-stage complication of cancer, but as a biologically and clinically heterogeneous disease requiring coordinated management. This article synthesises the fundamentals of BrM diagnosis and treatment, relevant to primary and urgent care settings. Treatment...

Melyda, Ahmad Ozairb, S. Lau et al. · Clinical medicine (London) · 0 citations