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P. Bušek

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Open access Sep 2026

FAP+ pericyte-like cells promote monocyte differentiation into tumor-associated macrophages in glioblastoma

It is found that FAP+ pericytes are linked to increased monocyte recruitment and differentiation into tumor-associated macrophages, particularly those with an M2-like, tumor-supportive phenotype, and Targeting this stromal population may offer new therapeutic avenues to reprogram tumor-associated immune responses in GB...

Magdalena Houdova Megova, C. Shard, B. Výmolová et al. · 0 citations
Open access Aug 2026

Brain metastasis‐associated fibroblasts shape the tumour microenvironment to enhance cancer cell invasion

A role for BrM‐CAFs is supported in shaping the brain metastatic microenvironment through ECM remodelling and the secretion of pro‐migratory mediators, promoting monocyte and cancer cell migration and enhancing cancer cell invasion.

B. Výmolová, L. Pfeiferová, T. Smetana et al. · 0 citations

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