Lack of Association Between CAT rs1001179 and SOD2 rs4880 Variants and Risk for Multiple Sclerosis
Objectives: Several lines of evidence point to a potential involvement of oxidative stress in the pathophysiology of multiple sclerosis (MS). Superoxide dismutase isoenzymes 1 and 2 (SOD1 and SOD2) and catalase (CAT) are key components of the enzymatic antioxidant defense system. Consequently, genetic variation in the...