Replicative and Air Pollution-Induced Senescence: Telomere Dysfunction, Mitochondrial Stress, and Modulatory Effects of Astragaloside IV in Endothelial and Vascular Smooth Muscle Cells
It is demonstrated that vascular senescence is governed by cell type-specific telomere-mitochondria interactions that are differentially modulated by FD, and the selective protective effects of AS-IV in endothelial cells support the development of telomere-targeted therapeutic strategies to mitigate pollution-induced v...