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Open access Sep 2026

Design, Synthesis, Characterization, and Anti-Breast Cancer Activity of Novel Pyrazole-Based Chalcones: Insights from Molecular Docking and DFT Studies

A novel series of 1-(furan-3-yl)-3-(1,3-diphenyl-1H-pyrazol-4-yl)prop-2-en-1-one was designed, synthesized, and characterized with the aim of developing potential anti-breast cancer agents. The synthesis was carried out by a Claisen-Schmidt condensation of 1,3-diphenyl-1H-pyrazole-4-carbaldehyde with 2-acetylfuran in t...

Ameen Ali Baig, P. Chavan, N. D. Satyanarayan · 0 citations

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