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P. Cooper

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Open access Sep 2026

ARID1A Mediates ROS-Induced Osteoclast Activation in TMJ Osteoarthritis.

Excessive osteoclast activation drives rapid subchondral bone destruction, serving as a critical early-stage event precipitating temporomandibular joint osteoarthritis (TMJ-OA). Although epigenetic remodeling is widely recognized as an important interface between pathological environmental signals and genomic response,...

Y.-L. Liu, J.-Y. Xu, Y.-Q. Wu et al. · 0 citations
Review Open access Aug 2026

Inflammation and Regeneration in the Dentine-Pulp Complex: Where are we now and where are we going?

INTRODUCTION To develop new regenerative endodontic procedures (REPs) we require an understanding of the basic biology of the dentin-pulp complex and its behavior in health, disease and healing. Clinicians and scientific research partnerships are essential for this field to advance. Translational-targeted tissue regene...

P. Cooper, Lara T. Friedlander, H. Hussaini et al. · 0 citations
Review Aug 2026

Precision Endodontics-Advancing Towards Omics-Guided Personalisation: A Narrative Review.

The concept of precision endodontics represents a potential evolution from conventional 'one-size-fits-all' approaches to more tailored interventions guided by extensive omics data, and the synergistic integration of omics and AI may provide a roadmap for developing the next generation of biologically individualised en...

M. Turky, P. Cooper, P. Dummer · 0 citations

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