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Review Open access Oct 2026

Sulforaphane as a Therapeutic Target for Sarcopenia in Type 2 Diabetes: Mechanistic Insights and Translational Evidence

Sulforaphane, a bioactive isothiocyanate abundant in cruciferous vegetables, has emerged as a potential multi-target therapeutic agent capable of mitigating these pathological processes. Here, using evidence from preclinical and clinical literature, we review the mechanistic and translational evidence linking sulforaph...

Ayanda Ngcobo, S. Shabalala, Nokulunga Hlengwa et al. · 0 citations
Review Open access Sep 2026

Oxidative lipoprotein remodelling in atherogenesis: Mechanistic insights and therapeutic potential.

Oxidative modification of lipoproteins, particularly oxidised low-density lipoprotein (oxLDL), is increasingly recognised as a critical driver of atherogenesis beyond conventional lipid measures. While low-density lipoprotein cholesterol (LDL-c) remains central to cardiovascular risk assessment, accumulating evidence i...

S. Mthembu, P. Dludla · 0 citations

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