Nigro-striatal deficits capture phenoconversion risk in isolated REM sleep behavior disorder
It is demonstrated that phenoconversion in iRBD relates similarly to dopaminergic denervation of the putamen and cell loss in the SN, which opens possibilities for using NM-MRI, which can simultaneously capture dopaminergic and noradrenergic deficits, as an alternative to nuclear imaging techniques when estimating phen...