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P. Falkai

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Open access Aug 2026

Psychometric validation of research domain criteria, general health, and clinical-psychosocial parts of the minimum dataset of the German Center for Mental Health—informing a Delphi process

This study evaluated the latent structure and conceptual validity of the Research Domain Criteria (RDoC), General Health, and Clinical/Psychosocial clusters of the German Center for Mental Health (DZPG) Minimum Data Set (MDS). It aimed to determine whether these clusters represent interpretable constructs and demonstra...

Bernd R. Förstner, S. Böttger, Timm Seegert et al. · 0 citations
Open access Aug 2026

Disentangling white matter correlates of symptom severity and general impairment in early psychosis.

Disentangling general impairment from psychosis-related symptom severity suggests potentially different underlying processes, and developing imaging biomarkers accounting for these processes may guide early detection strategies and targeted interventions.

N. Penzel, K. Cho, J. Seitz-Holland et al. · 0 citations
Open access Aug 2026

Investigating changes in the blood-brain barrier in schizophrenia spectrum disorders: design and methodology of a longitudinal dynamic contrast-enhanced MRI study

The IMPACT study aims to elucidate BBB alterations in SSDs and to support stratification approaches in precision psychiatry by providing a longitudinal, BBB-specific neuroimaging framework embedded in a deep phenotyping infrastructure.

A. Wendl, Amelie Zöllinger, Daniel Lukas et al. · 0 citations

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