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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

P. Giacobbe

h-index 45 View on Semantic Scholar

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Open access Sep 2026

47. Early improvement predicts subsequent antidepressant response to intravenous ketamine

Abstract Background Major depressive disorder (MDD) is a debilitating medical condition that places a significant psychological, social, and financial burden on the individuals and families of those affected. However, a third of individuals with MDD do not respond to standard treatments – diagnosed with treatment-resis...

O. Syed, F. Alam, P. Giacobbe · 0 citations
Open access Sep 2026

368. Relationship between childhood adversity and pre-operative structural MRI data in patients receiving deep brain stimulation of the subgenual cingulate cortex for treatment resistant depression

Abstract Background Adverse childhood experiences (ACEs) predict poorer response to treatments for major depressive disorder (MDD) including medications, psychotherapy, and their combination. ACEs are known to have effects on brain structure and function. Aims & Objectives We aim to characterize the relationship betwee...

E. Ng, G. Elias, J. Germann et al. · 0 citations
Open access Sep 2026

262. Impact of adverse childhood experiences on brain stimulation outcomes for depression

While ACEs were prevalent among patients with MDD receiving brain stimulation treatment, the presence of more ACEs was not associated with poorer outcomes with acute high frequency rTMS treatment or with SCC-DBS treatment with long-term follow-up.

E. Ng, E. Wong, N. Lipsman et al. · 0 citations

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