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Open access Sep 2026

Tocilizumab, atezolizumab, and stereotactic radiotherapy in recurrent glioblastoma: primary analysis of safety and efficacy of a phase 2 trial, NRG Oncology-BN010.

BACKGROUND Preclinical data suggest that fractionated stereotactic radiotherapy (FSRT) may sensitize immunologically-cold tumors to immune checkpoint inhibition by stimulating neoantigen release and that inhibition of interleukin-6 (IL-6) permits immunosuppressive tumor-associated macrophages to become immunostimulator...

Stephen J. Bagley, Mei-Yin C. Polley, R. Kotecha et al. · 0 citations
Sep 2026

Treatment intensity and survival benefit among older adults with glioblastoma: A population-based analysis.

BACKGROUND Older adults with glioblastoma (GBM) are frequently treated with de-escalated approaches. However, national trends in treatment intensity and the magnitude of absolute survival benefit across the older age spectrum remain unclear. METHODS We conducted a retrospective cohort study using the SEER database (2...

Jia-Nan Chen, Qiong Wu, Hannah M. Cardenas et al. · 0 citations

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