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Author

P. Grudnik

2 papers indexed here

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Open access Oct 2026

Mismetallation reveals metal tolerance and enhanced stability of human deoxyhypusine hydroxylase.

Hypusination is a unique post-translational modification found exclusively in eukaryotic translation factor 5A (eIF5A). In this reaction, a specific lysine residue in eIF5A is converted into hypusine residue. The modification comprises two enzymatic steps: a NAD-dependent deoxyhypusine synthase (DHS) transfers the 4-am...

Daniel Zakaszewski, P. Wilk, Elżbieta Wątor-Wilk et al. · 0 citations
Open access Sep 2026

Crystal structure of human NIF3-like protein reveals dynamic hexameric assembly with a single divalent metal binding site.

The first crystal structures of human NIF3 are presented, revealing a hexameric toroidal assembly with a central cavity gated by PII-like insertion domains and a half-capped state with asymmetric disorder of the insertion domains.

Elżbieta Wątor-Wilk, Krzysztof Żak, P. Wilk et al. · 0 citations

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