Author

P. Halfmann

2 papers indexed here

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Open access Aug 2026

Discovery of a 4′‐Azido Fleximer Nucleoside Analog With Broad‐Spectrum Antiviral Activity Against DENV, EBOV, and Other RNA Viruses

The ongoing emergence and reemergence of RNA viruses from multiple viral families highlights the urgent need for broad‐spectrum antiviral therapeutics. To address this issue, a series of 4′‐azido fleximer nucleoside analogs were synthesized and evaluated for broad‐spectrum antiviral activity against pathogens of epidem...

Kyle A. Davis, Ryan L. Slack, Thomas R. Foulkes et al. · ChemMedChem · 0 citations

Open access Aug 2026

A rapidly deployable CRISPR–Cas3 diagnostic platform for emerging RNA viruses

Rapidly converting viral genome information into deployable molecular tests remains a major challenge in outbreak preparedness. We developed CONAN-SWIFT (Simple Workflow for Isothermal Field Testing), a sequence-to-test platform that integrates computational assay design, reverse-transcription loop-mediated isothermal...

Jun Nakamura, Kaya Miyazaki-Iida, Shotaro Torii et al. · bioRxiv · 0 citations