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Open access Sep 2026

DUF4004 protein BacR (YhbD) of Bacillus subtilis is a regulator of bactofilin expression and interacts with bactofilins in a switch-like manner

Introduction DUF4004-containing proteins are found in a variety of bacteria. The only characterized member was shown to act as transcriptional repressor of genes involved in metabolism in Clostridium acetobutylicum. We have characterized the B. subtilis member of this protein family, encoded by the yhbD gene. The absen...

Kristin Velten, Patrik Brück, Shahla Alipour et al. · 0 citations
Open access Oct 2026

Selective Absence of Co-Inhibitory Receptor-Expressing CD4+ T Cells in Lungs of Obese House Dust Mite-Allergic C57BL/6 Mice.

BACKGROUND Asthma and obesity are highly prevalent chronic inflammatory diseases, the mutual pathomechanistic relationships of which have not been fully elucidated yet. We hypothesized that inflammatory mechanisms in obese adipose tissue influence the phenotype of an induced allergic airway inflammation (AAI) with alte...

S. Miethe, D. P. Potaczek, K. Pauck et al. · 0 citations

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