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Open access Oct 2026

Regional brain aging signatures predict mortality through neurovascular immune mechanisms.

Brain aging provides an integrative marker of systemic health, but whether regional patterns outperform whole-brain approaches remains unknown. Here, we show that regional brain age signatures achieve superior mortality prediction through identifiable neurovascular-immune mechanisms in 1,240 community-dwelling adults f...

P.-L. Lee, Yi-Long Huang, Chih-Kuang Liang et al. · 0 citations

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