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Open access Sep 2026

Lipid Metabolic Dysregulation Driven by OSMR Mutations Underlies Amyloidogenesis in Primary Localized Cutaneous Amyloidosis

ABSTRACT Background: Primary localized cutaneous amyloidosis (PLCA) is characterized by the deposition of amyloid material within the superficial dermis. Its origin and composition remain debated, including whether deposits derive from keratin filament degeneration or misfolded protein aggregation, and whether non‐prot...

Hui-Ting Liu, Wen Zheng, Chao Yang et al. · 0 citations

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