Summary Circular RNAs (circRNAs) are covalently closed non-coding RNAs characterized by high stability, tissue-specific expression, and important regulatory roles in gene expression and cellular pathways across cancer, neurodegenerative, cardiovascular, autoimmune, and infectious diseases. Their stability in biofluids...
A. Glovi, P. M. Kalligosfyri, A. Miglione et al.· iScience· 0 citations
Early detection of many diseases remains difficult because they often develop silently over the course of years. Circular RNAs are now at the forefront as biomarker candidates with a covalently closed structure, making them highly stable with exonuclease resistance and long half-lives. With their disease-specific expre...
A. Glovi, P. Kalligosfyri, A. Miglione et al.· Analytical Chemistry· 0 citations
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