Open access
Sep 2026
Design and in silico screening of novel isoniazid-based Schiff base derivatives followed by synthesis and biological evaluation of the lead compound against Mycobacterium tuberculosis H37Rv
The findings suggest that isoniazid-based Schiff base derivatives represent a promising scaffold for the development of new antitubercular agents, with SLB-5 emerging as a promising candidate for further investigation.
Shivani L. Bhuse, P. M. Patil, Rajat R. Durbule
· Discover Chemistry · 0 citations