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Author

P. Mastrokostas

4 papers indexed here

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Review Oct 2026

Impact of Regional Anesthesia on the Incidence and Detection of Acute Compartment Syndrome: A Systematic Review.

BACKGROUND Acute compartment syndrome (ACS) is a limb-threatening complication of orthopedic trauma, and the use of regional anesthesia (RA) remains controversial due to concerns that it may delay diagnosis. This systematic review evaluated whether RA influences the incidence or detection of ACS and whether current evi...

Rajendra Singh, Rohan Rajan, Ezekiel Kopilak et al. · 0 citations
Aug 2026

Administration of Preoperative Cryoneurolysis is Associated with Continued and Persistent Opioid Reduction and Improved Outcomes in Primary Total Knee Arthroplasty.

BACKGROUND Cryoneurolysis, a percutaneous technique applying targeted cold therapy to sensory nerves, has emerged as a non-opioid adjunct that may provide sustained analgesia after total knee arthroplasty (TKA). This study aimed to (1) determine whether preoperative cryoneurolysis reduces postoperative opioid use, (2)...

Mitchell K. Ng, Jennifer H. Lin, Andrew I. Spitzer et al. · 0 citations
Review Sep 2026

Periarticular Injection Cocktails for Pain Management After Total Knee Arthroplasty: A Systematic Review of Randomized Controlled Trials.

Multimodal PAI improves early postoperative outcomes after TKA, especially versus placebo, and the LB is a promising component, with some studies showing better pain control, lower opioid use, and higher patient satisfaction.

Mitchell K. Ng, Leonidas E. Mastrokostas, P. Mastrokostas et al. · 0 citations

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